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Epithalon
Longevity
99.3%
Purity
MOQ
Contact for MOQ
Lead Time
3~5 day
Storage
-20°C

Factory direct peptide supply

Epithalon

Epitalon / Epithalamin

99%+HPLC purity options
COABatch documents
3-5DFast preparation

Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland extract Epithalamin. It has been extensively studied for its ability to activate telomerase, the enzyme responsible for lengthening telomeres, which are associated with cellular aging. Research suggests it may extend cell lifespan, regulate melatonin production, and have antioxidant properties.

Key Benefits

Activates telomerase for telomere lengthening
Regulates melatonin and circadian rhythm
Antioxidant and cytoprotective effects
Supports immune system function

Available Sizes

Selected: 10 mg/vial (10 vials)
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Product Description

Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland extract Epithalamin. It has been extensively studied for its ability to activate telomerase, the enzyme responsible for lengthening telomeres, which are associated with cellular aging. Research suggests it may extend cell lifespan, regulate melatonin production, and have antioxidant properties.

CAS Number
307297-39-8
Appearance
White lyophilized powder
Solubility
Soluble in water or saline at ≥5 mg/mL
Storage
-20°C for long-term; 4°C for up to 8 weeks

Amino Acid Sequence

Ala-Glu-Asp-Gly

Molecular Information

Molecular FormulaC₁₄H₂₂N₄O₉
Molecular Weight390.35 Da
Purity MethodHPLC & MS

Technical Specifications

Product NameEpithalon
Alias / Trade NameEpitalon / Epithalamin
CAS Number307297-39-8
Molecular FormulaC₁₄H₂₂N₄O₉
Molecular Weight390.35 Da
Purity99.3% (by HPLC & MS)
AppearanceWhite lyophilized powder
SolubilitySoluble in water or saline at ≥5 mg/mL
Storage Conditions-20°C for long-term; 4°C for up to 8 weeks
Salt FormAcetate
Minimum Order QuantityContact for MOQ
Available Sizes10 mg/vial, 20 mg/vial, 50 mg/vial

Amino Acid Sequence

Ala-Glu-Asp-Gly

Certificate of Analysis

Batch-specific testing results

COA Report
Note: A batch-specific Certificate of Analysis (COA) is provided with every order. Contact us to request a sample COA for this product.

Factory supply workflow

From product name to confirmed quotation.

Send the product name, selected strength, quantity, purity requirement, packaging style and destination market. The sales team can confirm stock, MOQ, batch COA, HPLC/MS files, lead time and private label options.

01Confirm product

Product name, mg/vial, vial count and target quantity.

02Verify documents

Batch COA, HPLC, MS, appearance and storage conditions.

03Quote & packaging

Factory price, MOQ, label, box and custom brand support.

04Dispatch

Fast preparation with export support and shipment updates.

Related Research

Peer-reviewed scientific literature on Epithalon from PubMed, NEJM, The Lancet, and other authoritative sources.

1
Preclinical2003

Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells

Khavinson VKh, Bondarev IE, Butyugov AA.

Bulletin of Experimental Biology and Medicine, 135: 590–592 (2003)

Key Finding

Epithalon induced telomerase activity in human somatic cells that normally lack this enzyme, leading to measurable telomere elongation and extended cellular lifespan, suggesting a telomere-related mechanism at the cellular level.

2
Preclinical2020

Epithalon Increases the Lifespan of Drosophila melanogaster

Khavinson V, Diomede F, Mironova E, et al.

Nutrients, 12: 2550 (2020)

Key Finding

Epithalon treatment extended mean lifespan by 11–16% and maximum lifespan by 13% in Drosophila, while also improving reproductive capacity and oxidative stress resistance, supporting its longevity-promoting properties.

3
Observational2003

Peptide Bioregulators and Longevity: 35-Year Follow-Up Study of Patients Treated with Epithalon

Khavinson VKh, Morozov VG.

Neuroendocrinology Letters, 24: 233–240 (2003)

Key Finding

Patients receiving peptide bioregulator treatment including epithalon showed significantly reduced mortality rates (by 2.0–2.5×), lower cancer incidence, and improved immune function over the 35-year follow-up period compared to age-matched controls.