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TB-500
Performance
99.3%
Purity
MOQ
Contact for MOQ
Lead Time
3~5 day
Storage
-20°C

Factory direct peptide supply

TB-500

Thymosin Beta-4 Fragment

99%+HPLC purity options
COABatch documents
3-5DFast preparation

TB-500 is a synthetic peptide fragment of the naturally occurring protein Thymosin Beta-4. It plays a crucial role in actin regulation, cell migration, and tissue repair. Research has shown it promotes healing of heart, skin, eye, brain, spinal cord, and muscle tissue. It is widely used in performance and recovery research for its ability to reduce inflammation and promote flexibility.

Key Benefits

Studied for muscle-fiber development research
Supports accelerated tissue repair in research models
Improves flexibility and range of motion
Studied for wound-repair and tissue-remodeling research

Available Sizes

Selected: 5 mg/vial (10 vials)
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Product Description

TB-500 is a synthetic peptide fragment of the naturally occurring protein Thymosin Beta-4. It plays a crucial role in actin regulation, cell migration, and tissue repair. Research has shown it promotes healing of heart, skin, eye, brain, spinal cord, and muscle tissue. It is widely used in performance and recovery research for its ability to reduce inflammation and promote flexibility.

CAS Number
77591-33-4
Appearance
White lyophilized powder
Solubility
Soluble in water or bacteriostatic water at ≥1 mg/mL
Storage
-20°C for long-term; 4°C for up to 4 weeks

Amino Acid Sequence

Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-NH₂

Molecular Information

Molecular FormulaC₅₀H₈₃N₁₅O₁₅
Molecular Weight1114.25 Da
Purity MethodHPLC & MS

Technical Specifications

Product NameTB-500
Alias / Trade NameThymosin Beta-4 Fragment
CAS Number77591-33-4
Molecular FormulaC₅₀H₈₃N₁₅O₁₅
Molecular Weight1114.25 Da
Purity99.3% (by HPLC & MS)
AppearanceWhite lyophilized powder
SolubilitySoluble in water or bacteriostatic water at ≥1 mg/mL
Storage Conditions-20°C for long-term; 4°C for up to 4 weeks
Salt FormAcetate
Minimum Order QuantityContact for MOQ
Available Sizes5 mg/vial, 10 mg/vial

Amino Acid Sequence

Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-NH₂

Certificate of Analysis

Batch-specific testing results

COA Report
Note: A batch-specific Certificate of Analysis (COA) is provided with every order. Contact us to request a sample COA for this product.

Factory supply workflow

From product name to confirmed quotation.

Send the product name, selected strength, quantity, purity requirement, packaging style and destination market. The sales team can confirm stock, MOQ, batch COA, HPLC/MS files, lead time and private label options.

01Confirm product

Product name, mg/vial, vial count and target quantity.

02Verify documents

Batch COA, HPLC, MS, appearance and storage conditions.

03Quote & packaging

Factory price, MOQ, label, box and custom brand support.

04Dispatch

Fast preparation with export support and shipment updates.

Related Research

Peer-reviewed scientific literature on TB-500 from PubMed, NEJM, The Lancet, and other authoritative sources.

1
Preclinical2004

Research on Thymosin β4 in cardiac repair models

Bock-Marquette I, Saxena A, White MD, et al.

Nature, 432: 466–472 (2004)

Key Finding

Thymosin β4 significantly improved cardiac function post-infarction by activating dormant epicardial progenitor cells, promoting their migration and differentiation into cardiomyocytes, and reducing apoptosis in the infarct border zone.

2
Preclinical2003

Research on Thymosin Beta-4 in wound-repair models

Philp D, Badamchian M, Scheremeta B, et al.

Wound Repair and Regeneration, 11: 19–24 (2003)

Key Finding

Thymosin β4 was associated with wound-closure activity in both diabetic and aged mice by promoting keratinocyte migration, collagen deposition, and angiogenesis, suggesting therapeutic potential for impaired wound healing conditions.

3
Review2012

The Role of Thymosin Beta-4 in Tissue Repair and Regeneration: A Systematic Review

Goldstein AL, Hannappel E, Sosne G, Kleinman HK.

Annals of the New York Academy of Sciences, 1269: 129–137 (2012)

Key Finding

Thymosin β4 functions as a master regulator of tissue repair through its G-actin sequestration activity, promoting cell migration, reducing inflammation, stimulating angiogenesis, and activating progenitor cells in a coordinated healing response.